Ethyl Di-o-tolylphosphonoacetate [Horner-Emmons Reagent]
Ditolylphosphonoaceticacidethylester
CAS: 188945-41-7
Molecular Formula: C18H21O5P
Ethyl Di-o-tolylphosphonoacetate [Horner-Emmons Reagent] - Names and Identifiers
| Name | Ditolylphosphonoaceticacidethylester |
| Synonyms | ETHYL DI-O-TOLYLPHOSPHONOACETATE Ditolylphosphonoaceticacidethylester DI-O-TOLYLPHOSPHONOACETIC ACID ETHYL ESTER Di-o-tolylphosphonoacetic acid ethyl ester ethyl [bis(2-methylphenoxy)phosphoryl]acetate Ethyl Di-o-tolylphosphonoacetate [Horner-Emmons Reagent] Acetic acid, 2-[bis(2-methylphenoxy)phosphinyl]-, ethyl ester |
| CAS | 188945-41-7 |
| InChI | InChI=1/C18H21O5P/c1-4-21-18(19)13-24(20,22-16-11-7-5-9-14(16)2)23-17-12-8-6-10-15(17)3/h5-12H,4,13H2,1-3H3 |
Ethyl Di-o-tolylphosphonoacetate [Horner-Emmons Reagent] - Physico-chemical Properties
| Molecular Formula | C18H21O5P |
| Molar Mass | 348.33 |
| Density | 1.19 |
| Boling Point | 240 °C / 3mmHg |
| Flash Point | 241.623°C |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | clear liquid |
| Color | Colorless to Yellow to Orange |
| Storage Condition | Room Temprature |
| Refractive Index | 1.5330-1.5350 |
| MDL | MFCD01321166 |
Ethyl Di-o-tolylphosphonoacetate [Horner-Emmons Reagent] - Introduction
Pb, also known as LEPA, is an organophosphorus compound. It has the following properties and uses:
Nature:
-Appearance: colorless transparent liquid.
-Solubility: Soluble in organic solvents, such as ethanol and dimethylformamide.
-Stability: Stable at room temperature, but may decompose under high temperature or light.
-Combustibility: flammable, may burn in case of open flame or high temperature.
Use:
- LEPA can be used as a catalyst in organic synthesis, especially with good catalytic activity in carbonylation reactions.
-It can also be used to synthesize aluminum phosphate resin, and is widely used in surface coating, plastics and adhesives.
Method: The preparation of
is usually carried out through a three-step reaction:
1. Toluene reacts with phosphorous chloride to obtain Chlorinated Diphenyl phosphorus (DPP-Cl).
2. DPP-Cl reacts with sodium hydroxide to obtain diphenyl phosphate (DPPO).
3. Finally, DPPO is reacted with ethoxyacetic acid to form fluorene (LEPA).
Safety Information:
- LEPA is an organic phosphorus compound that may cause harm to the human body. Exposure to or inhalation of LEPA may cause irritation, allergy, or toxic symptoms.
-It is a flammable substance, avoid contact with fire sources.
-Use good ventilation and wear appropriate protective equipment, such as gloves and goggles.
-Be careful when storing and handling LEPA, and follow chemical safety procedures.
Nature:
-Appearance: colorless transparent liquid.
-Solubility: Soluble in organic solvents, such as ethanol and dimethylformamide.
-Stability: Stable at room temperature, but may decompose under high temperature or light.
-Combustibility: flammable, may burn in case of open flame or high temperature.
Use:
- LEPA can be used as a catalyst in organic synthesis, especially with good catalytic activity in carbonylation reactions.
-It can also be used to synthesize aluminum phosphate resin, and is widely used in surface coating, plastics and adhesives.
Method: The preparation of
is usually carried out through a three-step reaction:
1. Toluene reacts with phosphorous chloride to obtain Chlorinated Diphenyl phosphorus (DPP-Cl).
2. DPP-Cl reacts with sodium hydroxide to obtain diphenyl phosphate (DPPO).
3. Finally, DPPO is reacted with ethoxyacetic acid to form fluorene (LEPA).
Safety Information:
- LEPA is an organic phosphorus compound that may cause harm to the human body. Exposure to or inhalation of LEPA may cause irritation, allergy, or toxic symptoms.
-It is a flammable substance, avoid contact with fire sources.
-Use good ventilation and wear appropriate protective equipment, such as gloves and goggles.
-Be careful when storing and handling LEPA, and follow chemical safety procedures.
Last Update：2024-04-09 21:00:56
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Product Name: Di-o-Tolylphosphonoacetic Acid Ethyl Ester Visit Supplier Webpage Request for quotation
CAS: 188945-41-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 188945-41-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
Ethyl Di-o-tolylphosphonoacetate [Horner-Emmons Reagent]
Boronic acid, (4-fluoro-3-methylphenyl)- (9CI)
4-CHLORO-3-NITROBENZOIC ACID METHYL ESTER
Boronic acid, (4-fluoro-3-methylphenyl)- (9CI)
4-CHLORO-3-NITROBENZOIC ACID METHYL ESTER